Title: Improving nonstoquastic quantum annealing with spin-reversal transformations

Abstract: Nonstoquastic Hamiltonians are hard to simulate due to the sign problem in quantum Monte Carlo simulation. It is however unclear whether nonstoquasticity can lead to advantage in quantum annealing. Here we show that YY-interaction between the qubits makes the adiabatic path during quantum annealing, and therefore the performance, dependent on spin-reversal transformations. With the right choice of spin-reversal transformation, a nonstoquastic Hamiltonian with YY-interaction can outperform stoquastic Hamiltonians with similar parameters. We introduce an optimization protocol to determine the optimal transformation and discuss the effect of suboptimality.