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Condensed Matter > Soft Condensed Matter

Title: Transverse fluctuations control the assembly of semiflexible filaments

Abstract: The kinetics of the assembly of semiflexible filaments through end-to-end annealing is key to the structure of the cytoskeleton, but is not understood. We analyze this problem through scaling theory and simulations, and uncover a regime where filaments ends find each other through bending fluctuations without the need for the whole filament to diffuse. This results in a very substantial speed-up of assembly in physiological regimes, and could help understand the dynamics of actin and intermediate filaments in biological processes such as wound healing and cell division.
Comments: Main: 5 pages, 4 figures. Supplementary: 10 pages, 9 figures. To be published in Physical Review Letters
Subjects: Soft Condensed Matter (cond-mat.soft); Materials Science (cond-mat.mtrl-sci); Statistical Mechanics (cond-mat.stat-mech); Biological Physics (physics.bio-ph)
Journal reference: Phys. Rev. Lett. 131, 228401 (2023)
DOI: 10.1103/PhysRevLett.131.228401
Cite as: arXiv:2303.03088 [cond-mat.soft]
  (or arXiv:2303.03088v2 [cond-mat.soft] for this version)

Submission history

From: Valerio Sorichetti [view email]
[v1] Mon, 6 Mar 2023 13:03:02 GMT (2524kb,D)
[v2] Tue, 31 Oct 2023 13:04:14 GMT (2891kb,D)

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