Title: Saturability of the Quantum Cramér-Rao Bound in Multiparameter Quantum Estimation at the Single-Copy Level

Abstract: The quantum Cram\'{e}r-Rao bound (QCRB) as the ultimate lower bound for precision in quantum parameter estimation is only known to be saturable in the multiparameter setting in special cases and under conditions such as full or average commutavity of the symmetric logarithmic derivatives (SLDs) associated with the parameters. Moreover, for general mixed states, collective measurements over infinitely many identical copies of the quantum state are generally required to attain the QCRB. In the important and experimentally relevant single-copy scenario, a necessary condition for saturating the QCRB in the multiparameter setting for general mixed states is the so-called partial commutativity condition on the SLDs. However, it is not known if this condition is also sufficient. This paper derives new necessary conditions that imply partial commutativity and are almost sufficient. It is shown that together with another condition they become sufficient for saturability of the QCRB in the multiparameter single-copy case. Moreover, when the sufficient conditions are satisfied an optimal measurement saturating the QCRB can be chosen to be projective and explicitly characterized. An example is developed to illustrate the case of a multiparameter quantum state where the conditions derived herein are satisfied and can be explicitly verified.