Title: Endhered patterns in matchings and RNA

Abstract: An endhered (end-adhered) pattern is a subset of arcs in matchings, such that the corresponding starting points are consecutive and the same holds for the ending points. Such patterns are in one-to-one correspondence with the permutations. We focus on the occurrence frequency of such patterns in matchings and real-world RNA structures with pseudoknots. We present combinatorial results related to the distribution and asymptotic behavior of the pattern 21, which corresponds to two consecutive stacked bonds frequently encountered in RNA, and the pattern 12, representing the archetypal minimal pseudoknot. We show that in matchings these two patterns are equidistributed, which is quite different from what we can find in real-world RNAs. We also examine the distribution of endhered patterns of size 3, showing how the patterns change under the transformation called endhered twist. Finally, we compute the distributions of endhered patterns of size 2 and 3 in real-world secondary RNA structures with pseudoknots and discuss possible outcomes of our study.